Cialis (Tadalifil citrate), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Cialis works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function. Cialis is much longer lasting than Viagra. Effects can be felt anywhere between 36-48 hours.
The FDA approved Cialis as a medicine for ED on November 21, 2003. It is available through prescription for those who are diagnosed with impotence. In 1998, ICOS Corporation, and Eli Lilly and Company, began manufacturing Cialis, which is available orally in 5mg, 10mg and 20mg tablets. It is also widely available by many research companies and underground labs.
Tadalafil improves erectile function significantly, possibly increase testosterone through increased sexual activity, and is very safe.
There are limited side effects associated with its use. The most common side effects are headache, upset stomach, back pain, and muscle aches, and usually subside with in a few hours.
In a six month study on men with erectile dysfunction ranging from mild to severe, 20 mgs of Cialis or placebo was administered to subjects as needed. It was discovered that Tadalafil improved ED compared to placebo. Ability to achieve erection and sucessful intercourse was 73% greater in those reciving Cialis verses the placebo group (1). Cialis was administered three times per week for an extended period of time, it was found to be extremely safe and very limited side effects were experienced, if any (1).
Cialis was also linked to increased testosterone levels in a one month study where testosterone levels were found to be significantly higher at the end of the month, due to increased sexual activity(2).
How ironic. Some of the compounds which can be used to make men more physically attractive to women (Deca, Tren, etc…) can cause sexual dysfunction. Even more ironic is that many of the compounds which make them more attractive to us (Beer, Whiskey, etc…) can also do this.
Tadalafil is a drug used to treat male erectile dysfunction (impotence). It was developed by the biotechnology firm ICOS and marketed worldwide by Eli Lilly and Company under the brand name Cialis.
In the United States, tadalafil has Food and Drug Administration approval and became available in December, 2003 as the third impotence pill after sildenafil (Viagra) and vardenafil (Levitra). Due to its 36-hour effect it is also known as the weekend pill. It should be noted that the drug has not been formally studied in regard to multiple sexual attempts during a 36 hour period.
Tadalafil is also currently undergoing Phase III clinical trials for the treatment of pulmonary hypertension.